1H-Indole-2,3-dione is used in the synthesis of spirooxindoles and also in the synthesis of bisquinoline derivatives displaying antitumor activity. Isatin is a potential biomarker for stress, found in the blood.
Khalafi-Nezhad, A. et al.: ACS Comb. Sci., 15, 512 (2013); Li, S. et al.: Eur. J. Med. Chem., 64, 62 (2013); see Chem. and Eng. News p. 31 May18, 2015
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