Hexahydro-1,3-isobenzofurandione is used in the synthesis of hypotensive agents, pyridazinones. Also used in the synthesis of selective PDE4 inhibitors.
Curran, W. et al.: J. Med. Chem., 17, 273 (1974); Van der Mey, M. et al.: J. Med. Chem., 44, 2511 (2001);
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