Dimethyl Succinate is a reagent to evaluate the pharmacokinetic parameters of quinoline acylsulfonamides as potent and selective antagonists of EP4 receptor which is used for the treatment for chronic inflammation.
Burch, J.D, et al.: Bioorg. Med. Chem. Lett., 18, 2048 (2008); Flower, R., et al.: Nat. Rev. Drug Disc., 2, 179 (2003)
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