(8S,10S)-10-(((2R,4S,S,S)-4-氨基-- | (8S,10S)-10-(((2R,4S,S,S)-4-Amino | - 亚薄世界杯试剂

：纯度：98% CAS：

英文名称：(8S,10S)-10-(((2R,4S,S,S)-4-Amino--hydroxy--methyltetrahydro-2H-pyran-2-yl)oxy)-,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-,-dione hydrochloride (Doxorubicin Impurity)

规格	目录价格	上海	安徽	武汉	成都	北方	深圳	会员价格	数量
2mg	请询价	--	--	--	--	--	--	--	- +
0mg	请询价	--	--	--	--	--	--	--	- +
100mg	请询价	--	--	--	--	--	--	--	- +
20mg	请询价	--	--	--	--	--	--	--	- +

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产品名称：(8S,10S)-10-(((2R,4S,R,S)-4-Amino--hydroxy--methyltetrahydro-2H-pyran-2-yl)oxy)-,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-,-dione hydrochloride (Doxorubicin Impurity) 纯度：98%

：18444

CAS号：390-09-1

￥ ƺĩñĞññ /2mg

￥ ŦŦƂĞññ /0mg

￥ ƂǿñĩĞññ /100mg

￥ ĴƺŷñĞññ /20mg

￥ ǿƂñƂĞññ /1g

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基本信息
属性
计算化学
参考文献
安全信息

英文名称

(8S,10S)-10-(((2R,4S,S,S)-4-Amino--hydroxy--methyltetrahydro-2H-pyran-2-yl)oxy)-,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-,-dione hydrochloride (Doxorubicin Impurity)

英文别称

中文别称

亚德里亚霉素盐酸盐

Smiles Code

OC1=C(C(C2=CC=CC(OC)=C2C3=O)=O)C3=C(O)C4=C1C[C@](C(CO)=O)(O)C[C@@H]4O[C@H]C[C@@H]([C@@H]([C@@H](O)C)O)N.Cl

分子式

C27H30ClNO11

纯度

98%

阿霉素是一种插入DNA并抑制大分子生物合成的抗肿瘤抗生素。由于拓扑异构酶 II 的抑制，DNA 复制被牵引。它是逆转录酶和 RNA 聚合酶的抑制剂，是一种免疫抑制剂。

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20.07

[1]. Akshaya Kumar Swain, et al. Polymer Stabilized Fe3O4-Graphene as an Amphiphilic Drug Carrier for Thermo-Chemotherapy of Cancer. ACS Appl Mater Interfaces. 201 Apr 22;7(1):8013-22.

[2]. Ana C Moreira, et al. Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblasts. Biochim Biophys Acta. 2014 Dec;1842( Pt A):248-78.

[3]. Christine Egger, et al. Adriamycin-induced nephropathy in rats: functional and cellular effects characterized by MRI. J Magn Reson Imaging. 201 Mar;41(3):829-40.

[4]. Denis Fourches, et al. Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chem Res Toxicol. 2010 Jan;23(1):171-83.

[]. Jing Cao, et al. Loading and release mechanism of red clover necrotic mosaic virus derived plant viral nanoparticles for drug delivery of doxorubicin. Small. 2014 Dec 29;10(24):-3.